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SmartStax® PRO with RNAi Technology

SmartStax® PRO with RNAi Technology

SmartStax® PRO with RNAi Technology is the next generation of protection against an ongoing threat: corn rootworm. Built on the strong foundation of SmartStax® Technology, SmartStax PRO Technology introduces a third mode of action that offers improved corn rootworm control over a range of pressures for the strongest biotech defense from Bayer.


An Industry First for Corn Built on the Proven Benefits of SmartStax® Technology

SmartStax® PRO Technology combines the proven benefits of SmartStax® Technology with an additional, unique RNAi-based mode of action — becoming the first product with three modes of action for corn rootworm control.

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Protects Against Above- and Below-Ground Pests

In addition to corn rootworm, SmartStax® PRO Technology will also provide protection against above-ground pests including European corn borer, southwestern corn borer, fall armyworm, black cutworm and corn earworm.

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The Advantage of RNAi Technology

Bayer is the first to develop RNAi technology to combat corn rootworm, which offers a new and unique third mode of action against the pest. By interfering with a corn rootworm’s ability to create a specific protein critical to its own survival, RNAi technology effectively causes mortality after ingestion.

Because RNAi technology works differently than a soil-applied insecticide or Bt traits to control corn rootworm, it can increase your corn’s ability to defend itself against the billion dollar bug.

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Targeting Corn Rootworm

SmartStax PRO Technology contains the two proven Bt traits found in SmartStax Technology to target corn rootworm. In addition, the introduction of RNAi Technology adds an entirely new mode of action against this insect. RNAi works by interfering in a naturally occurring process within the corn rootworm to stop the production of a specific protein vital to their life cycle. Together, these three modes of action form a powerful combination against this top threat to corn.

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3X Greater Root Node Protection

From Corn Rootworm -vs. Qrome® Products-

2021 and 2022 Seasons**

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A Defense Unlike Any Other

SmartStax PRO Technology offers our strongest biotech defense against corn rootworm on the market. But as we continue to track the early signs of a growing corn rootworm threat, SmartStax PRO Technology offers our strongest biotech defense against corn rootworm pressure while still providing protection against above-ground pests and tolerance to glyphosate and glufosinate herbicide applications.

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Looking to the Future

In preparation for the commercial launch of SmartStax PRO Technology, on-farm trials were conducted in 2021. Limited volumes of SmartStax PRO Technology products were available to farmers in 2022. During 2023 and beyond, volumes will ramp up to give farmers in areas dealing with the risk of corn rootworm the highest level of protection. Ask your dealer about SmartStax PRO Technology and its availability in your area

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Answers to Your Trait Questions


More Than A Rewards Program


Insect Forecast

*Based upon 2021-2022 Bayer internal trials comparing leading corn rootworm technologies in fields with moderate to heavy corn rootworm pressure.

**69 2021 & 2022 Bayer Trials in the corn belt (KS, CO, NE, IA, IL, ND, SD, OH, MN, & WI) vs Qrome® products in the 95-115 RM range with comparable trait packages.​

ALWAYS READ AND FOLLOW PESTICIDE LABEL DIRECTIONS. SmartStax® PRO Technology is not currently available for commercial sale or commercial planting. Commercialization is dependent on multiple factors, including successful conclusion of the regulatory process. The information presented herein is provided for educational purposes only and is not and shall not be construed as an offer to sell. Bayer, the Bayer Cross and SmartStax® are registered trademarks of Bayer Group ©2021 Bayer Group. All rights reserved.